James Gallagher, BBC News (September 26, 2012)
"Mice with brittle skin, which tears off in order to escape predators, may offer clues to healing wounds without scarring, according to US researchers.
"Some African spiny mice lost up to 60% of the skin from their backs, says the study published in the journal Nature.
"Unlike wounds in other mammals, the skin then rapidly healed and regrew hairs rather than forming a scar...."
Some critters, like salamanders, can regrow limbs. Mammals regrow scar tissue: handy for quick repairs, not so good as a replacement part. These oddball mice are an exception, at least where skin is involved.
The good news is that scientists may be able to figure out how the African spiny mice grow new skin, and develop ways for mammals to grow other sorts of tissue.
The bad news, sort of, is that someone will probably get upset about the process. Those mice look cute, and might not like losing skin from their backs: which the Lemming is concerned about; but learning how to regrow lost limbs or damaged organs would be nice, too. There's a balance, somewhere, between the welfare of mice and people. There are knee-jerk responses to new ideas, too: and that's another topic.
The Lemming found a rather detailed and boring discussion about the spiny mice on the NIH website:
More:
- "Could animal research lead to 'self-repairing skin'?"
PubMed Health, U.S. Library of Medicine, National Institutes of Health (September 27, 2012)
- "Mutant Mice Shed Light on Intestinal Bacteria"
(October 14, 2011) - " 'Cancer Causes Cell Phones!' - or, not"
(July 18, 2011) - "Hands off Driving, Driving With Your Brain, and All That"
(March 4, 2011) - "Livestock, Food, and Attack of the Clones"
(August 7, 2010) - "Glow-in-the-Dark Flashing Tattoos? Prosthetics With Neural Interfaces? They're Coming"
(November 20, 2009)
3 comments:
I'm more interesting in how they lose their skin without the wound becoming infected. Especially since the last time I heard about mice regrowing parts the scientists involved accomplished it in part by turning off part of the critters' immune systems.
welcome to lions den
Good points, Brigid. The resources I found didn't go into that. My guess is that there's a microbe-resistant film left in place.
But that's a guess.
(Wow - took me long enough to respond!)
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